This provocative study forges new and creative connections between Deleuzian philosophy and contemporary film studies.

In this paper, we view creativity through the lens of innovation, a concept familiar to archaeologists across a range of contexts and theoretical perspectives. Most attempts to understand ancient innovation thus far, we argue, have been limited by their lack of capacity to cope with the multiple scales of innovation: Those that track widespread changes, like the beginnings of metallurgy, fail to account for the changes experiences by individual craftspeople; those that do justice to the details of the micro-scale, with (...) ‘thick’ description, cannot well explain the regional adoption of new practices. Here we develop an intermediary position, at the meso-scale, which we hope can serve to integrate these different scales. It is based on the notions that all innovation entails learning (and hence cognitive transformations) and that learning is very often supported at this meso-scale, through ‘communities of practice’. Drawing on the ethno-archaeological literature in particular, we emphasise how learning is a process of embodied cognition. Our archaeological case study is then drawn from the Bronze Age east Mediterranean, where a striking innovation in pottery making — the use of rotative kinetic energy via the potter’s wheel — sees a very uneven uptake from region to region over the course of many centuries. We propose certain differences in community organization from one region to another that might account for such variation in the adoption of an innovation, with the island of Crete in particular seeing a much more stable trajectory of adoption than many of its neighbouring areas. (shrink)

In this analysis we discuss the change in criteria for triage of patients during three different phases of a pandemic like COVID-19, seen from the critical care point of view. Availability of critical care beds has become a hot topic, and in many countries, we have seen a huge increase in the provision of temporary intensive care bed capacity. However, there is a limit where the hospitals may run out of resources to provide critical care, which is heavily dependent on (...) trained staff, just-in-time supply chains for clinical consumables and drugs and advanced equipment. In the first phase, we can still do clinical prioritisation and decision-making as usual, based on the need for intensive care and prognostication: what are the odds for a good result with regard to survival and quality of life. In the next, the resources are mostly available, but the system is stressed by many patients arriving over a short time period and auxiliary beds in different places in the hospital being used. We may have to abandon admittance of patients with doubtful prognosis. In the last phase, usual medical triage and priority setting may not be sufficient to decrease inflow and there may not be enough intensive care unit beds available. In this phase different criteria must be applied using a utilitarian approach for triage. We argue that this is an important transition where society, and not physicians, must provide guidance to support triage that is no longer based on medical priorities alone. (shrink)

Obese people consume significantly greater amounts of health resources. This study set out to determine if health resource utilization by obese people decreases after losing weight in a comprehensive medically supervized weight management programme. Four hundred and fifty-six patients enrolled in a single-centred, multifaceted weight loss programme in a universal health care system were studied. Patient information was anonymously linked with administrative databases to measure health resource utilization for 1 year before and after the programme. Mean body mass index (BMI) (...) decreased by more than 15%. The mean annual physician visits (pre = 9.6, post = 9.4) did not change significantly after the programme. However, patients saw a significantly fewer number of different physicians per year following the programme (pre = 4.5, post = 3.9; P < 0.001). Mean annual number of emergency visits (pre = 0.2; post = 0.2) and hospital admissions (pre = 0.05; post = 0.08) did not change. Neither baseline BMI, nor its change during the programme, influenced changes in health resource utilization. Our study suggests that weight loss in a supervized weight management programme does not necessarily decrease short-term health resource utilization. Further study is required to determine if patients who maintain their weight loss experience a decrease in health utilization. (shrink)

Today’s students are accustomed to a world where information is available on-demand, anywhere and anytime. They bring this expectation to their academic world where they want to work cooperatively and flexibly, using the modern information processing tools and access with which they are familiar. New hardware platforms such as e-Readers and tablet computers have made substantial inroads in the consumer market. E-Readers are becoming more prevalent in universities – replacing the need for physical textbooks, lecturing notes and other academic documents. (...) Many universities are now running pilot programs, while some are already using e-Readers. Tablet computers, apart from their ability to read, edit or create various types of information documents, also offer additional features such as collaborative and social networking services. This empirical research project investigated student perspectives on the educational use of e-Readers and tablets within the University of Cape Town. A questionnaire was distributed to a significant portion of the student population and stratified according to seniority and faculty. Quantitative data was gathered and analysed on themes ranging from awareness to preferences to facilitating conditions around e-Readers within the academic environment. The students sent a clear signal: that they are keen to embrace these new technologies and the advantages they offer. E-Books can be updated automatically and downloaded to e-Readers instantly from almost anywhere in the world. Students feel they would benefit greatly through the use of e-Readers and many believe they are set to replace books completely. Having access to a portable library of information in their backpacks would benefit both students and the environment. However, there are a number of barriers to the comprehensive introduction of these technologies, including the cost of the devices; cost, rights and file format of e-books; the need for a critical mass of textbooks available in digital format and device characteristics such as battery life, and ubiquitous Wi-Fi access. (shrink)

After more than a century of research on glycolysis, we have detailed descriptions of its molecular organization, but despite this wealth of knowledge, linking the enzyme properties to metabolic pathway behavior remains challenging. These challenges arise from multi‐layered regulation and the context and time dependence of component functions. However, when viewed as a system that functions according to the principles of supply and demand, a simplifying theoretical framework can be applied to study its regulation logic and to assess the coherence (...) of experimental interpretations. These principles are universally applicable, as they emphasize the common metabolic tasks of glycolysis: the provision of free‐energy carriers, and precursors for biosynthesis and stress‐related compounds. Here we will review the regulation of multi‐tasking by glycolysis and consider how an understanding of this central metabolic pathway can be pursued using general principles, rather than focusing on the biochemical details of constituent components. (shrink)

Analysis of the Freudian interpretation of the Oedipus myth which functions as a paradigm case for the Oedipus complex reveals the neglect of certain essential details. Moreover, it appears that clinical material as presented by psychoanalysts in support of the Oedipus complex is strongly biased towards the acceptance of the hypothesis that the Oedipus complex is a universal phenomenon. In this article arguments are given that cast serious doubt on the validity of psychoanalytic theory. The author proposes a new interpretation (...) which explains the putative Oedipal conflict in the child as the projection of parental aggression on the child. (shrink)

This article chronicles the process used to transform a content-driven chemistry lab course into a course focused on developing critical-thinking skills. In general, the process described includes the following: 1) determining the needs of the students, 2) understanding the history of the course, 3) identifying some specific critical thinking skills that could be developed in the course, 4) considering how the skills can be taught developmentally, 5) defining criteria for the skills at different levels; 6) revising the lab manual to (...) include explicit critical-thinking definitions, directions and criteria for students, and 7) designing assessments of the students’ critical thinking abilities as defined and practiced in the lab. Six critical thinking skills (testing hypotheses, distinguishing between observationsand inferences, identifying assumptions, drawing conclusions supported by data, evaluating conclusions, and considering alternative explanations of data) were incorporated into the course. The lab manual displaying the results of this transformation is available by request from either the author or the journal editor. (shrink)

In Coldness and Cruelty, Deleuze remarks that masochism may be reflected on from three perspectives: as a pleasure–pain alliance, as an enactment of humiliation and slavery, and as a consideration of the enslavement of contractual relations. Later Deleuze and Guattari consider masochism in terms of an ontology of desire – in terms of virtuality rather than extensity. I argue that while the actualisation of pain might be considered secondary, and is oftentimes portrayed as incidental in popular depictions, it also constitutes (...) the exhaustive/exhausted and refrain functions of masochism so that the masochist might be thought of as the figure of exhaustion. (shrink)

1. Introduction. It is an amazing thing that, unlike pebbles, clouds and stars, the smallest building stones of Nature—the electrons, the protons and the neutrons—are all completely uniform. There seems to be a necessity in Nature for systems of a very special form, and one can wonder now what kind of necessity this is. I believe that this can only be a mathematical necessity, that consequently the principle of Nature is a mathematical one. How else could Nature obey the mathematical (...) laws of physics if it were not because of her own principle? It can be argued that these mathematical laws, like Newtonian mechanics, the classical theory of electromagnetism and the quantum theory of the electron are all some form of beginner's luck, and that continued investigation will reveal Nature as more and more mysterious and irrational. If that were true, one might as well give up the pursuit of physics completely! But on one hand modern physics has discovered what we believe to be the elementary particles of the material world, and on the other hand it comes out that at least a part of these elementary forms obey mathematic laws to a very high degree of accuracy. (shrink)

Extending a strategy previously used by Clancy, Schacter, McNally, and Pitman , we administered a neutral and a trauma-related version of the Deese–Roediger–McDermott paradigm to a sample of women reporting recovered or repressed memories of childhood sexual abuse , women reporting having always remembered their abuse , and women reporting no history of abuse . We found that individuals reporting recovered memories of CSA are more prone than other participants to falsely recalling and recognizing neutral words that were never presented. (...) Moreover, our study is the first to show that this finding even held when trauma-related material was involved. Correlational analyses revealed that fantasy proneness, but not self-reported traumatic experiences and dissociative symptoms were related to false recall and false recognition. (shrink)

The literature on thought experiments has been mainly concernedwith thought experiments that are directed at a theory, be it in aconstructive or a destructive manner. This has led somephilosophers to argue that all thought experiments can beformulated as arguments. The aim of this paper is to drawattention to a type of thought experiment that is not directed ata theory, but fulfills a specific function within a theory. Suchthought experiments are referred to as functional thoughtexperiments, and they are routinely used in (...) applied statistics. An example is given from frequentist statistics, where a thoughtexperiment is required to establish the probability space. It isconcluded that (a) not all thought experiments can be formulated asarguments, and (b) the role of thought experiments is more generaland more important to scientific reasoning than has previouslybeen recognized. (shrink)

In this article a case is made for the importance of a previously overlooked phenomenon, physical empathy orcompathy,defined as the physical manifestation of caregiver distress that occurs in the presence of a patient in physical pain or distress. According to the similarity of a caregiver's response to the original symptoms, there can be four types of compathetic response: identical, initiated, transferred, and converted. Controlling for the compathetic response may involve narrowing one's focus and/or changing caregiver attitudes. Finally, we argue that (...) while the compathetic response may be beneficial to the caregiving relationship, enabling the provision of appropriate and adequate humane treatment and care, the caregiver must at times shield against the compathetic response in order to provide care. (shrink)

Developing countries face numerous barriers to conducting effective and efficient ethics reviews of international collaborative research. In addition to potentially overlooking important scientific and ethical considerations, inadequate or insufficiently trained ethics committees may insist on unwarranted changes to protocols that can impair a study's scientific or ethical validity. Moreover, poorly functioning review systems can impose substantial delays on the commencement of research, which needlessly undermine the development of new interventions for urgent medical needs. In response to these concerns, the Drugs (...) for Neglected Diseases Initiative, an independent nonprofit organization founded by a coalition of public sector and international organizations, developed a mechanism to facilitate more effective and efficient host country ethics review for a study of the use of fexinidazole for the treatment of late stage African Trypanosomiasis. The project involved the implementation of a novel ‘pre-review’ process of ethical oversight, conducted by an ad hoc committee of ethics committee representatives from African and European countries, in collaboration with internationally recognized scientific experts. This article examines the process and outcomes of this collaborative process. (shrink)

Exploring Practical Knowledge investigates professional practices from a hermeneutic perspective. The book presents, discusses and applies notions such as practical knowledge, practical wisdom, tacit knowledge, and normativity to the professional lifeworld. These contributions focus on both specific practices and more general questions concerning theories and investigations of practice. This volume comes as the result of a cooperation of three research centres: The two Centres for Practical Knowledge in Bodø, Norway and in Södertörn, Sweden, as well as the Research Group Value-Oriented (...) Professionalisation at the University of Applied Sciences in Utrecht, the Netherlands. It offers empirical studies of professionals as well as discussing the underlying theories, approaches and methods of exploring practical knowledge - including the limits to any articulation of these aspects of professional action. In contrast to the objectivist paradigm that otherwise dominates professional studies, each chapter presents central perspectives and possibilities drawing from humanistic and interdiscipkinary research traditions. The book explores professions in a style accessible to scholars and practitioners alike. It is interesting for those studying practices within these professions and for vocational studies in education, social work, health care, police work, journalism, etc. (shrink)